Immune Regulation

Basophils account for only around 1% of white blood cells but play a role in allergy defense and stimulate antibodies against pathogens and parasitic organisms (such as ticks and worms) that cause injury or infection.

Lymphocyte levels can reveal a number of conditions, including autoimmunity, bone marrow disorders, kidney disease, gastrointestinal disorders, and more. The role of lymphocytes in the body’s immune defense is so crucial that abnormal levels can weaken the body, leading to severe illness or impairing its ability to fight off infections. The test includes both percentage and absolute levels.

Testing the quantity of neutrophils helps detect damage caused by inflammatory disorders (such as rheumatoid arthritis and gout), infections (both acute and chronic), certain cancers (such as myelocytic leukemia), and physical stressors (including eclampsia in pregnant women, injury, and burns). Neutrophils are key patrols and first responders in the immune system, attacking antigens they encounter. The test includes both percentage and absolute levels.

hs-CRP is revelatory in one’s overall health as it relates to the risk of inflammation-related diseases. Chronic inflammation is linked to every major disease: heart disease (even before symptoms occur), type 2 diabetes, cancer, high blood pressure, Alzheimer’s, depression, all autoimmune diseases, and severe allergic reactions like asthma.

Eosinophils are recruited to inflamed areas of the body to trap substances, kill infected cells, viruses, parasites, and bacteria, and help tame an allergic response. Testing can reveal issues in the digestive tract, specifically the esophagus, and includes both percentage and absolute levels.

Like other white blood cells (WBCs), monocytes help the immune system destroy invaders and also facilitate healing and repair. Abnormal levels can indicate bacterial infections, virus or fungus, stress, chronic infections, or autoimmune disorders. The test includes both percentage and absolute levels.

A healthy WBC baseline over time correlates with the body’s ability to fight off diseases and other hazards. Prolonged abnormalities can negatively affect biological age by impairing healing and increasing the risk of illness.

C4a is part of the complement system—a network of proteins that enhances immune defense by fighting infections and clearing damaged cells—and plays a key role in regulating inflammation. Monitoring its activity can help assess its role in autoimmune diseases chronic infections and inflammatory conditions.

* This blood test can be added for an extra charge and is not included in the $499 membership.